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Zollinger-Ellison Syndrome
Alternate Names : Gastrinoma, Z-E Syndrome
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Treatment
A class of acid-suppressing medications called proton pump inhibitors (for example, omeprazole, lansoprazole) is now first line treatment of Zollinger-Ellison syndrome. These drugs reduce acid production by the stomach dramatically and promote healing of ulcers in the stomach and small bowel. They also provide relief of abdominal pain and diarrhea. Another class of acid-suppressing medications called H-2 blockers may also be used (for example, cimetidine, ranitidine). The H-2 blockers are less potent than proton pump inhibitors.
Surgical removal of a single gastrinoma may be attempted if there is no evidence that it has spread to other organs (such as lymph nodes or the liver). Surgery on the stomach (gastrectomy) to control acid production is rarely necessary today.
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• Definition
• Overview, Causes, & Risk Factors
• Symptoms & Signs
• Prevention
• Diagnosis & Tests
• Treatment
• Prognosis
• Complications
• Calling Your Health Care Provider
• Pictures & Images
Topics that might be of interest to you Diseases & Conditions
• Tumor
Tests & Exams
• Abdominal CT Scan
• Gastrin
• Secretin Stimulation Test
Other Topics
• Abdominal Pain
• Diarrhea
• Vomiting Blood
Review Date : 5/9/2002
Reviewed By : Stephanie Fish, M.D., Division of Endocrinology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
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