Unstable Angina

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Unstable Angina Treatment

An individual experiencing unstable angina usually requires rest and hospitalization to prevent complications.

A cornerstone of therapy for unstable angina is antiplatelet medication (to prevent platelet aggregation, which is the initial event in the blood circulation leading to clot formation within a vessel). One antiplatelet agent widely used is aspirin. More recently, a medication called clopidogrel has shown in clinical studies to be even more effective than aspirin in reducing the likelihood of heart attacks. Clopidogrel and aspirin may be used together. They are also often administered during heart attacks.

Heparin and nitroglycerin are also given during unstable angina, often sublingually (under the tongue) or intravenously (IV). Other medications include beta-blockers, calcium channel blockers, anti-anxiety medications, and medications to control blood pressure and abnormal heart rhythms.

Surgery may be recommended. CABG (coronary artery bypass grafting) or PTCA (balloon angioplasty), often with the implantation of a stent, may be necessary.