TSI
Alternate Names : Thyroid Stimulating Immunoglobulin, TSH Receptor Antibody
Definition A test that measures the amount of TSI in the blood.
Why is the Test Performed?
This test may be performed as part of the diagnostic work-up of Graves' disease.
The TSI is an antibody directed against the receptor for TSH on the thyroid gland. This antibody interacts with the receptor and mimics the action of the pituitary hormone TSH. The TSI stimulates the gland to secrete excessive amounts of thyroid hormone. TSI measurements are also performed in the third trimester of pregnancy to predict neonatal Graves' disease.
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