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Thrombotic Thrombocytopenic Purpura
Alternate Names : TTP
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Treatment
Plasmapheresis, or plasma exchange, is used to remove unwanted substances from the blood (large von Willebran protein complexes), and to replace the missing protease. Blood is withdrawn from the patient as for a blood donation.
Then the plasma portion of the blood is passed through a cell separator. The remaining portion of the blood is saved, reconstituted with fresh plasma, and returned to the patient as a blood transfusion.
In thrombotic thrombocytopenic purpura, this treatment is repeated daily until blood tests show improvement. People who do not respond to this treatment, or have frequent recurrences, may require the removal of the spleen, corticosteroids, or other immune suppression.
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• Definition
• Overview, Causes, & Risk Factors
• Symptoms & Signs
• Prevention
• Diagnosis & Tests
• Treatment
• Prognosis
• Complications
• Calling Your Health Care Provider
• Pictures & Images
Topics that might be of interest to you Diseases & Conditions
• Acute Kidney Failure
• Anemia
• Blood Clots
• Hemolytic-Uremic Syndrome (HUS)
• Stroke
Tests & Exams
• Bilirubin
• Biopsy
• Blood Smear
• CBC
• Creatinine - Serum
• Platelet Count
• Pulse
• RBC Count
• Urinalysis
Other Topics
• Bleeding Into the Skin
• Breathing Difficulty
• Chronic
• Confusion
• Consciousness - Decreased
• Fatigue
• Fever
• Headache
• Jaundice - Yellow Skin
• Paleness
• Protein in Diet
• Purpura
• Weakness
Review Date : 10/13/2003
Reviewed By : Corey Cutler, M.D., M.P.H., F.R.C.P.C, Department of Medical Oncology, Dana-Farber Cancer Institute; Instructor in Medicine, Harvard University, Boston, MA. Review provided by VeriMed Healthcare Network.
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