Thrombolytic Therapy (Tissue Plasminogen Activator - TPA)
Alternate Names : Activase Thrombolytic Agent, Alteplase, Clot-Dissolving Agents, Reperfusion Therapy, Reteplase, Tenecteplase, TPA
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Stroke
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A stroke involves loss of brain functions caused by a loss of blood circulation to areas of the brain. The blockage usually occurs when a clot or piece of atherosclerotic plaque breaks away from another area of the body and lodges within the vasculature of the brain.
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Thrombus
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A thrombus is a blood clot that forms in a vessel and remains there. An embolism is a clot that travels from the site where it formed to another location in the body. Thrombi or emboli can lodge in a blood vessel and block the flow of blood in that location depriving tissues of normal blood flow and oxygen. This can result in damage, destruction (infarction), or even death of the tissues (necrosis) in that area.
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