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Testicular Feminization
Alternate Names : Androgen Insensitivity Syndrome
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Diagnosis & Tests
Signs may include:
- vagina present but no cervix or uterus
- normal female breast development
- testes in the inguinal canal, labia, or abdomen
- inguinal hernia with palpable gonad
Tests:
- Testosterone levels -- in the male range
- XY Karyotyping -- the presence of one X and one Y sex chromosome indicates male gender
- Luteinizing hormone (LH) levels -- high
- Follicle-stimulating hormone (FSH) levels -- normal
- Sonogram -- shows an absent uterus or intra-abdominal testes
- Androgen receptor studies (research setting) may confirm the syndrome
Tests which may distinguish androgen resistance from androgen deficiency (or 5-alpha reductase deficiency):
- Increased basal and hCG-induced testosterone
- Normal dihydrotestosterone
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• Definition
• Overview, Causes, & Risk Factors
• Symptoms & Signs
• Diagnosis & Tests
• Treatment
• Prognosis
• Complications
• Calling Your Health Care Provider
• Pictures & Images
Review Date : 10/6/2003
Reviewed By : Tarun Jain, M.D., Endocrinology & Infertility Division, Brigham and Women's Hospital, Boston, MA. Review provided by VeriMed Healthcare Network.
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