The Tensilon test is a method to help diagnose myasthenia gravis.

The test helps diagnosis myasthenia gravis, may aid in telling the difference between myasthenic and other similar neurological conditions, and may be used to monitor oral anticholinesterase therapy.

A drug called Tensilon (also called edrophonium) or a dummy medicine (inactive placebo) is given during this test. The health care provider gives the appropriate one through one of your veins (intravenously, through an IV). You may also be given a medication called atropine before receiving Tensilon so that you do not know you are receiving the drug.

You will be asked to perform some repetitive muscular movements such as crossing and uncrossing your legs or getting up from a sitting position in a chair. Particular attention will be paid to whether your muscle strength is improved by the Tensilon.

The test may be repeated and additional Tensilon may be given to help tell the difference between myasthenia gravis and other conditions.

No special preparation is usually necessary. However, you should follow any dietary restrictions or other directions prescribed by your health care provider.

You will feel a sharp prick as the IV needle is inserted. The drug may cause a feeling of a churning of the stomach or a slight feeling of increased heart rate, especially if Atropine is not given first.