AllRefer Health - Sugar-Water Hemolysis Test (Sucrose Hemolysis Test)

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You are here : AllRefer.com > Health > Tests & Exams > Sugar-Water Hemolysis Test

Sugar-Water Hemolysis Test


•	Definition
•	Why is the Test Performed?
•	How is the Test Performed?
•	How to Prepare for the Test?
•	How will the Test Feel?
•	Normal Values
•	What do Abnormal Results Mean?
•	Special Considerations
•	Risks
•	Go To Main Page

Alternate Names : Sucrose Hemolysis Test

Definition

This is a blood test to detect increased fragility of red blood cells by swelling them in low-salt solution.

Why is the Test Performed?

This test is ordered for suspected paroxysmal nocturnal hemoglobinuria (PNH), and for any hemolytic anemia of unkown origin. PNH red blood cells are unusually susceptible to complement (a component of the body's defense mechanism).

When a low-salt solution containing sucrose (sugar) is added to these cells, the complement is activated, binds to the cells, and bursts them.

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• Definition
• Why is the Test Performed?
• How is the Test Performed?
• How to Prepare for the Test?
• How will the Test Feel?
• Normal Values
• What do Abnormal Results Mean?
• Special Considerations
• Risks

Review Date : 9/14/2003
Reviewed By : Corey Cutler, M.D., M.P.H., F.R.C.P.C., Department of Medical Oncology, Dana-Farber Cancer Institute; Instructor in Medicine, Harvard University, Boston, MA. Review provided by VeriMed Healthcare Network.

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