Simian Crease
Alternate Names : Single Palmar Crease
Definition A simian crease is a single crease extending across the palm of the hand. People normally have three creases in their palms.
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Overview & Considerations
Prominent creases (called "flexion creases") appear on the palms of the hands and soles of the feet. The palm normally has three flexion creases. Sometimes, the two horizontal creases fuse to form a single crease, called a single palmar crease or a "simian crease."
Many structures develop in the fetus in the first few months of gestation. Palmar creases develop early, by the 11th to 12th week of life. Abnormalities in palmar creases may indicate problems with early development and be associated with other developmental disorders like Down's Syndrome.
However, a single palmar crease or simian crease appears in approximately 1 out of 30 people. Males are twice as likely as females to have this condition.
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