Simian Crease

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What to Expect at your Health Care Provider's Office

An infant with a simian crease generally has other symptoms and signs that, when taken together, define a specific syndrome or condition. Diagnosis of that condition is based on a family history, medical history, and thorough physical evaluation.

Medical history questions documenting a simian crease in detail may include:

• Is there a family history of Down syndrome or other disorder associated with a simian crease?
• Have other family members had a simian crease and no other abnormality?
• What was the pregnancy like?
• Did the mother use alcohol while pregnant?
• What other symptoms or physical abnormalities are also present?

Note: This finding is usually discovered by the health care provider.

The history and physical examination findings will determine whether further laboratory and diagnostic procedures are necessary.