Sex-Linked Dominant

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Chances of inheriting a trait

For an X-linked dominant disorder: If the father carries the abnormal X gene, all of his daughters will inherit the disease and none of the sons will have the disease. If the mother carries the abnormal X gene half of all their children (daughters and sons) will inherit the disease tendency.

In other words, if it is assumed that 4 children are produced (2 male and 2 female), the mother is a carrier (1 abnormal X, she has disease), and the father is normal, the STATISTICAL expectation is for:

• 2 children (1 girl and 1 boy) with disease
• 2 children (1 girl and 1 boy) normal

• 2 girls with disease
• 2 normal boys

This does not mean that children WILL necessarily be affected.