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Secondary Systemic Amyloid
Definition Secondary systemic amyloid is a disorder in which insoluble protein fibers become deposited in tissues and organs impairing their function. It is found in association with chronic infection or chronic inflammatory disease.
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Overview, Causes, & Risk Factors
The exact mechanism that causes secondary systemic amyloid is unknown. The risk factors are the presence of chronic inflammatory or infectious diseases. Secondary systemic amyloid occurs in association with multiple myeloma, and chronic conditions (those that last for 5 or more years) such as: rheumatoid arthritis, tuberculosis, long term paraplegia, bronchiectasis, cystic fibrosis, chronic osteomyelitis, recurrent pyogenic (involving pus) skin infection/abscess, decubitus ulcers, chronic renal dialysis, juvenile chronic arthritis, systemic lupus erythematosus, Reiter's syndrome, ankylosing spondylitis, Hodgkin's disease, Sjogren's syndrome, and hairy cell leukemia.
Symptoms are the same as in primary amyloidosis. The symptoms are related to the organs that become affected with the deposits. The affected organs exhibit reduced function.
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Definition Overview, Causes, & Risk Factors Symptoms & Signs Prevention Diagnosis & Tests Treatment Prognosis Complications Calling Your Health Care Provider
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Topics that might be of interest to you Diseases & Conditions
Abscess Acute Kidney Failure Ankylosing Spondylitis Arrhythmias Bronchiectasis Cardiomyopathy Carpal Tunnel Syndrome Cystic Fibrosis Hairy Cell Leukemia Heart Failure Hodgkin's Lymphoma Multiple Myeloma Nephrotic Syndrome Osteomyelitis Primary Amyloidosis Pulmonary Tuberculosis Reiter's Syndrome Rheumatoid Arthritis Sjogren Syndrome Systemic Lupus Erythematosus
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Abdominal Ultrasound Biopsy Bone Marrow Biopsy BUN Creatinine - Serum Dialysis ECG Echocardiogram Nerve Conduction Velocity Urinalysis Urinary Casts
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Bleeding Breathing Difficulty Chronic Endocrine Fat Fatigue Heart Murmurs and Other Sounds Hepatomegaly Mucosa Numbness and Tingling Physical Examination Protein in Diet Renal Respiratory Subcutaneous Swallowing Difficulty Swelling Systemic Weight Loss - Unintentional
Review Date : 6/5/2003
Reviewed By : Ezra E. W. Cohen, M.D., Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL. Review provided by VeriMed Healthcare Network.
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