Sclerosing cholangitis
Alternate Names : Primary sclerosing cholangitis, PSC
Definition
Sclerosing cholangitis refers to swelling (inflammation), scarring, and destruction of the bile ducts inside and outside of the liver.
Overview, Causes, & Risk Factors
In this condition, the bile ducts inside and outside the liver become narrowed and scarred. The cause is often unknown. The disease is often seen in patients who have:
Genetic factors may also be responsible. Sclerosing cholangitis occurs more often in men than women. This disorder is rare in children. Sclerosing cholangitis may also be caused by: - Choledocholithiasis
- Toxicity from chemicals, copper, bile acids
- Infections in the liver, gallbladder, and bile ducts
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