There may be no symptoms. When symptoms occur, they can involve almost any part or organ system in your body.

Almost all patients have lung or chest symptoms:

• Dry cough
• Shortness of breath
• Discomfort behind your breast bone
• Abnormal breath sounds (such as rales)

Symptoms of general discomfort or uneasiness often occur:

• Ill feeling (malaise)
• Fatigue (one of the most common symptoms in children)
• Fever
• Weight loss (one of the most common symptoms in children)
• Joint achiness or pain (arthralgia)

Skin symptoms:

• Skin rashes
• Old scars become more raised
• Raised, red, firm skin sores (erythema nodosum), almost always on the front part of the lower legs
• Skin lesions
• Hair loss

Nervous system (neurological) and vision changes:

• Headache
• Seizures
• Weakness or paralysis (palsy) on one side of the face
• Eye burning, itching, and discharge
• Symptoms of uveitis
• Decreased tearing

Other symptoms of this disease:

• Enlarged lymph glands (armpit lump)
• Enlarged liver
• Enlarged spleen
• Dry mouth
• Nosebleed

Often the disease is found in patients with no symptoms who have an abnormal chest x-ray.

Different imaging tests may help diagnose sarcoidosis:

• Chest x-ray to see if the lungs are involved or lymph nodes are enlarged
• CT scan
• Lung gallium (Ga.) scan

Biopsies of different tissues may be done:

• Lymph node biopsy
• Skin lesion biopsy
• Bronchoscopy to perform a biopsy
• Open lung biopsy
• Mediastinoscopy with biopsy
• Liver biopsy
• Kidney biopsy
• Nerve biopsy
• Heart biopsy

This disease may also alter the results of the following lab tests:

• CBC
• Chem-7 or chem-20
• Quantitative immunoglobulins (nephelometry)
• PTH
• Serum phosphorus
• Immunoelectrophoresis - serum
• Calcium - urine
• Calcium - ionized
• Calcium - serum
• Liver function tests