Distal renal tubular acidosis
Alternate Names : Renal tubular acidosis - distal, Renal tubular acidosis type I, Type I RTA, RTA - distal, Classical RTA
Definition
Distal renal tubular acidosis is a disease that occurs when the kidneys don't remove acid properly into the urine, leaving the blood too acidic (called acidosis).
Overview, Causes, & Risk Factors
Your kidneys normally regulate your body's pH by removing acids from the blood and discarding them into the urine. Distal renal tubular acidosis (Type I RTA) is caused by a defect in the kidney tubes that causes acid to build up in the bloodstream. Type I RTA is caused by a variety of conditions, including:
- Amyloidosis
- Fabry disease
- Sickle cell disease
- Sjogren syndrome
- Systemic lupus erythematosus
- Wilson disease
- Use of certain drugs such as amphotericin B, lithium, and analgesics
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