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Renal Papillary Necrosis
Alternate Names : Necrosis - Renal Papillae, Renal Medullary Necrosis
DefinitionRenal papillary necrosis is a disorder of the kidneys involving death of some or all of the renal papillae.
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Overview, Causes, & Risk Factors
The renal papillae are the areas of the kidney where the openings from the collecting ducts enter the renal pelvis. Necrosis (tissue death) of this area may result in impairment of the kidneys ability to concentrate the urine with ensuing polyuria (increased urine volume, usually in excess of 3 liters per day) and nocturia (frequent urination at night).
The necrotic tissue may be sloughed off, and it may be present in the urine as tissue, or the tissue may obstruct the renal pelvis or the ureter. Presence of necrotic tissue in the urine increases the risk of urinary tract infections. Necrosis of multiple papillae in the kidney can lead to eventual failure of that kidney.
Renal papillary necrosis is most commonly associated with analgesic nephropathy, diabetic nephropathy, renal transplant rejection, urinary tract obstruction, kidney infections and sickle cell anemia. Sickle cell anemia is a common cause of renal papillary necrosis in children.
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• Definition
• Overview, Causes, & Risk Factors
• Symptoms & Signs
• Prevention
• Diagnosis & Tests
• Treatment
• Prognosis
• Complications
• Calling Your Health Care Provider
• Pictures & Images
Topics that might be of interest to you Diseases & Conditions
• Acute Bilateral Obstructive Uropathy
• Acute Kidney Failure
• Acute Unilateral Obstructive Uropathy
• Analgesic Nephropathy
• Chronic Bilateral Obstructive Uropathy
• Chronic Renal Failure
• Chronic Unilateral Obstructive Uropathy
• Diabetes
• Diabetic Nephropathy
• Hyperkalemia
• Hypovolemic Shock
• Metabolic Acidosis
• Obstructive Uropathy
• Sickle Cell Anemia
• Urinary Tract Infection
• Urinary Tract Infection - Chronic or Recurrent
Tests & Exams
• Intravenous Pyelogram
• Urinalysis
• Urinary Casts
Other Topics
• Acute
• Back Pain - Low
• Chronic
• Flank Pain
• Necrosis
• Pain Medications
• Palpation
• Renal
• Urinary Frequency/Urgency
• Urinary Incontinence
• Urination - Difficulty with Flow
• Urination - Painful
• Urine - Bloody
Review Date : 10/17/2003
Reviewed By : Irfan A. Agha, M.D., Department of Medicine, Renal Division, St. Louis University, St. Louis, MO. Review provided by VeriMed Healthcare Network.
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