Progressive multifocal leukoencephalopathy (PML)

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Progressive multifocal leukoencephalopathy

Alternate Names : PML

Definition

Progressive multifocal leukoencephalopathy (PML) is a rare disorder that damages the material (myelin) that covers and protects nerves in the white matter of the brain.

Overview, Causes, & Risk Factors

The JC virus (JCV) causes PML. This virus is found in a lot of people, but usually does not cause symptoms. However, it triggers PML in people who have poor immune function (immunocompromised).

The disease occurs in 4% of adults with AIDS.

Pictures & Images

Gray and white matter of the brain

Leukoencephalopathy

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Progressive multifocal leukoencephalopathy : Definition
Progressive multifocal leukoencephalopathy : Overview, Causes, & Risk Factors
Progressive multifocal leukoencephalopathy : Symptoms & Signs
Progressive multifocal leukoencephalopathy : Diagnosis & Tests
Progressive multifocal leukoencephalopathy : Treatment
Progressive multifocal leukoencephalopathy : Prognosis (Expectations)
Progressive multifocal leukoencephalopathy : References
Progressive multifocal leukoencephalopathy : Pictures & Images
Gray and white matter of the brain
Leukoencephalopathy

Review Date : 2/13/2008
Reviewed By : Luc Jasmin, MD, PhD, Departments of Anatomy & Neurological Surgery, University of California, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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