Primary myelofibrosis (Myelofibrosis, Idiopathic myelofibrosis, Myeloid metaplasia, Agnogenic myeloid metaplasia)

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Primary myelofibrosis

Alternate Names : Myelofibrosis, Idiopathic myelofibrosis, Myeloid metaplasia, Agnogenic myeloid metaplasia

Definition

Primary myelofibrosis is a disorder of the bone marrow, in which the marrow is replaced by fibrous (scar) tissue.

Overview, Causes, & Risk Factors

The cause of primary myelofibrosis is unknown. Scarring of the bone marrow causes blood to form in abnormal sites, such as the liver and spleen. This causes swelling of these organs.

There are no known risk factors.

The disorder usually develops slowly in people over age 50.

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Primary myelofibrosis : Definition
Primary myelofibrosis : Overview, Causes, & Risk Factors
Primary myelofibrosis : Symptoms & Signs
Primary myelofibrosis : Diagnosis & Tests
Primary myelofibrosis : Treatment
Primary myelofibrosis : Prognosis (Expectations)
Primary myelofibrosis : Complications
Primary myelofibrosis : Calling Your Health Care Provider
Primary myelofibrosis : Prevention
Primary myelofibrosis : References

Review Date : 7/11/2008
Reviewed By : David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and James R. Mason, MD, Oncologist, Director, Blood and Marrow Transplantation Program and Stem Cell Processing Lab, Scripps Clinic, Torrey Pines, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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