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Post-Streptococcal GN
Alternate Names : Glomerulonephritis - Post-Streptococcal, Post-Infectious Glomerulonephritis
Definition Post-streptococcal GN is a disorder of the kidneys. It involves inflammation of the glomeruli after infection with certain strains of the streptococcus bacterium.
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Overview, Causes, & Risk Factors
Post-streptococcal glomerulonephritis is now an uncommon form of glomerulonephritis. It is the result of an infection, not of the kidneys, but of a remote site such as the skin or pharynx, with a specific type of Group A hemolytic streptococcus bacterium.
As a consequence of trapping immune complexes (formed from streptococcal antigen, antibodies, and complement) in the glomeruli of the kidneys, the glomeruli become inflamed, causing inefficient filtering and excreting function by the kidneys. Protein and blood may be present in the urine, and excess fluid commonly accumulates in the body. Hypertension characteristically is present.
The disorder is now less common because of the more common use of antibiotics for predisposing infections. It may occur in people of any age, especially children 6 to 10 years old. The disorder may develop 1 to 2 weeks after a throat infection, and 3 to 4 weeks after a skin infection. Although skin and throat infections are not uncommon in children, post infectious GN is a rare complication of these infections.
Risk factors include having a recent history of sore throat, strep throat, streptococcal skin infections (such as impetigo), and other streptococcal infections.
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Definition Overview, Causes, & Risk Factors Symptoms & Signs Prevention Diagnosis & Tests Treatment Prognosis Complications Calling Your Health Care Provider
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Topics that might be of interest to you Diseases & Conditions
Acute Kidney Failure Chronic Glomerulonephritis Chronic Renal Failure End-Stage Kidney Disease Glomerulonephritis Heart Failure Hyperkalemia Hypertension Impetigo Nephrotic Syndrome Pulmonary Edema Strep Throat
Tests & Exams
ASO Titer Biopsy Blood Pressure Complement Protein - Urine Renal Biopsy Sodium - Urine Urinalysis Urinary Casts
Other Topics
Abdomen - Swollen Antibody Antigen Auscultation Cough Facial Swelling Foot, Leg, and Ankle Swelling High Blood Pressure Joint Pain Peripheral Protein in Diet Sore Throat Swelling Urine - Bloody Urine Output - Decreased
Review Date : 1/19/2002
Reviewed By : Andrew T. Koren, M.D., Department of Nephrology, NYU-Mount Sinai Medical Center, New York, NY. Review provided by VeriMed Healthcare Network.
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