Polycythemia Vera
Alternate Names : Cryptogenic Polycythemia, Erythremia, Erythrocytosis Megalosplenica, Myeloproliferative Disorder, Osler's Disease, Polycythemia Rubra Vera, Polycythemia with Chronic Cyanosis - Myelopathic Polycythemia, Primary Polycythemia, Splenomegalic Polycythemia, Vaquez's Disease
DefinitionPolycythemia vera is an abnormal increase in blood cells (primarily red blood cells) resulting from excess production by the bone marrow.
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Overview, Causes, & Risk Factors
Polycythemia vera is an acquired disorder of the bone marrow that causes the overproduction of all three blood cell lines: white blood cells, red blood cells, and platelets.
It is a rare disease that occurs more frequently in men than women, and rarely in patients under 40 years old. It is not known what causes polycythemia vera.
The disease usually develops slowly, and most patients do not experience any problems related to the disease after being diagnosed. However, the abnormal bone marrow cells may begin to grow uncontrollably in some patients leading to acute myelogenous leukemia.
Patients with polycythemia vera also have an increased tendency to form blood clots that can result in strokes or heart attacks. Some patients may experience abnormal bleeding because their platelets are abnormal.
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