Pick's Disease
Alternate Names : Arnold Pick's Disease, Circumscribed Brain Atrophy, Focal Cerebral Atrophy, Fronto-Temporal Dementia, Lobar Sclerosis
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Pick's Disease Symptoms & Signs
Movement/coordination difficulties (apraxia) -- may be one of the earliest symptoms
Mood changes, personality changes:
- striking loss of concern and lack of anxiety
- loss of initiative
- flat affect (does not display any emotion)
- indecision
- inappropriate mood
- lack of spontaneity
- decreased interest in daily living activities
- impaired judgment
Behavior changes:
- excessive manual exploration of the environment
- withdrawal from social interaction
- inability to function or interact in social or personal situations
- inability to maintain employment
- decreased ability to function in self care
- behavior that is inappropriate relative to the environment
Language changes:
- echolalia (repetition of anything spoken to the person)
- speech is incomprehensible jargon
- aphasia (decreased language ability, difficulty speaking or understanding speech)
- inability to comprehend speech
- difficulty finding a word
- shrinking vocabulary
- inability to speak
- inability to repeat a phrase
- poor enunciation
- decreased ability to read or write
- inability to name objects
Other changes:
- loss of cognitive/intellectual skills
- specific disorders of problem solving/learning:
- inability to generalize
- loss of abstract thinking
- impaired calculating ability
- inability to learn
- weakness
- increased muscle tone
- urinary incontinence
- progressive dementia
- memory loss
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