Foot, Leg, and Ankle Swelling

See all Pictures & Images

Foot, Leg, and Ankle Swelling: Common Causes

Foot, leg, and ankle swelling is common with the following situations:

• Prolonged standing
• Long airplane flights or automobile rides
• Menstrual periods (for some women)
• Pregnancy -- excessive swelling may be a sign of pre-eclampsia (a serious condition that includes high blood pressure and swelling; sometimes called toxemia)
• Being overweight
• Increased age
• Injury or trauma to your ankle or foot

Swelling of the legs may be a sign of heart failure, kidney failure, or liver failure. In each of these conditions, there is too much fluid in your body.

Other conditions that can cause swelling to one or both legs include:

• Blood clot
• Infection of the leg
• Venous insufficiency (when the veins in your legs are unable to adequately pump blood back to the heart)
• Varicose veins
• Burns including sunburn
• Insect bite or sting
• Starvation or malnutrition
• Surgery to your leg or foot

Certain medications may also cause your legs to swell:

• Hormones like estrogen (in birth control pills or hormone replacement therapy) and testosterone
• A group of blood pressure lowering drugs called calcium channel blockers (especially nifedipine, but also amlodipine, diltiazem, felodipine, and verapamil)
• Steroids
• Certain antidepressants, namely MAO inhibitors (such as phenelzine and tranylcypromine) and tricyclics (including nortriptyline, desipramine, and amitriptyline)