|
|
Paget's Disease
Alternate Names : Osteitis Deformans
Definition A metabolic bone disease that involves bone destruction and regrowth that results in deformity.
Pictures & Images
 See all Pictures & Images
Overview, Causes, & Risk Factors
The cause of Paget's disease is unknown. Early viral infection and genetic causes have been theorized. The disease occurs worldwide, but is more common in Europe, Australia, and New Zealand where it is seen in up to 5% of the elderly population.
The disease is characterized by excessive breakdown of bone tissue, followed by abnormal bone formation. The new bone is structurally enlarged, but weakened and filled with new blood vessels.
The disease may localize to one or two areas within the skeleton, or become widespread. Frequently, the pelvis, femur, tibia, vertebrae, clavicle, or humerus are involved. The skull may enlarge head size and cause hearing loss, if the cranial nerves are damaged by the bone growth.
Today's Top News Stories | • | Teen Birth Rate Up in 26 States in 2006 - Jan 07, 2009, 14:00
Highest rates in South, Southwest; lowest rates in Northeast, government reports. | • | Clinical Trials Update: Jan. 7, 2009 - Jan 07, 2009, 09:58
- Hypertension (High Blood Pressure)
- Attention Deficit/Hyperactivity Disorder (ADHD - Pediatric)
- Memory Loss
| • | Europe Unlikely to Meet Measles Goals: Report - Jan 07, 2009, 09:00
Suboptimum vaccination rates cast doubt on ability to eliminate disease by 2010. | • | More 'Screen Time' Linked to Poor Fitness in Girls - Jan 07, 2009, 12:00
But teenage boys don't seem to be as susceptible, study suggests. | • | Heart Drug May Be a Cancer Fighter - Jan 07, 2009, 14:00
Digoxin, used to treat heart failure, slowed cell growth, study says. |
|
Jump to another section
• Definition
• Paget's Disease Overview, Causes, & Risk Factors
• Paget's Disease Symptoms & Signs
• Paget's Disease Diagnosis & Tests
• Paget's Disease Treatment
• Paget's Disease Prognosis
• Paget's Disease Complications
• Paget's Disease Support Groups
• Calling Your Health Care Provider
• Pictures & Images
Topics that might be of interest to you Diseases & Conditions
• Heart Failure
• Osteomyelitis
• Spinal Stenosis
Tests & Exams
• ALP
• ALP (Alkaline Phosphatase) Isoenzyme
• Bone Scan
• Bone X-Ray
• Serum Calcium
Other Topics
• Bone Pain or Tenderness
• Broken Bone
• Headache
• Hearing Loss
• Joint Pain
• Neck Pain
• Pain Medications
Review Date : 3/19/2002
Reviewed By : Todd T. Brown, M.D., Division of Endocrinology and Metabolism, Johns Hopkins University, Baltimore, MD. Review provided by VeriMed Healthcare Network.
|
|
