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Ovarian overproduction of androgens
Symptoms & Signs
Hyperandrogenism: - Acne
- Amenorrhea (absence of menstrual periods)
- Changes in female body contours
- Decrease in breast size
- Increase in body hair in a male pattern (hirsutism)
- Oily skin
Virilization: - Clitoromegaly (enlargement of the clitoris)
- Deepening of the voice
- Increase in muscle mass
- Temporal balding (thinning hair and hair loss)
Diagnosis & Tests
- 17-hydroxyprogesterone
- ACTH test
- CT scan
- Glucose and insulin level tests
- Pelvic ultrasound
- Prolactin (if periods are infrequent or absent)
- Testosterone
- TSH (if there is balding)
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Review Date : 5/12/2008
Reviewed By : Susan Storck, MD, FACOG, Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine; Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Redmond, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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