Multiple System Atrophy
Alternate Names : Neurologic Orthostatic Hypotension, Parkinson's Plus Syndrome, Shy-Drager Syndrome, Shy-McGee-Drager Syndrome
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Symptoms & Signs
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Dizziness or fainting when arising or after standing still
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Impotence
- Loss of sweating of any part of the body
- Loss of control of bowels or bladder
- Vision changes, decreased or blurred vision
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Muscle rigidity
- Stiffness
- Difficulty bending arms or legs
- Posture difficulties: may be unstable, stooped, or slumped over
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Movement difficulties
- Slow movements
- Difficulty beginning to walk or initiating any voluntary movement
- Small steps followed by the need to run to maintain balance
- Freezing of movement when the movement is stopped, unable to resume movement
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Muscle aches and pains (myalgia)
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Tremors: may be present in varying degrees or may not be present
- May occur at rest or at any time
- May become severe enough to interfere with activities
- May be worse when tired, excited, or stressed
- Finger-thumb rubbing (pill rolling tremor): may be present
- May occur with any action such as holding a cup or other eating utensils
- Changes in facial expression
- Reduced ability to show facial expressions
- "Mask" appearance to face
- Staring
- May be unable to close mouth
- Voice and/or speech changes
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Difficulty chewing or swallowing (occasionally)
- Loss of fine motor skills
- Difficulty writing: may be small and illegible
- Difficulty eating
- Difficulty with any activity that requires small movements
- Frequent falls
- Mild decline in intellectual function (may occur)
Additional symptoms that may be associated with this disease:
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