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Multiple Endocrine Neoplasia (MEN) I
Alternate Names : Wermer's Syndrome
Definition
Multiple Endocrine Neoplasia (MEN) I is a hereditary disorder in which one or more of the following glands develop excess normal tissue (hyperplasia) or adenoma (tumor): the parathyroid, the pancreas, the pituitary, and rarely, the adrenals and thyroid gland.
These are all endocrine glands, which produce and secrete hormones into the blood or lymph systems.
Pictures & Images
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Overview, Causes, & Risk Factors
The cause of MEN I is genetic. Tumors of various glands appear in the same person, but not necessarily at the same time. The disorder is inherited, may occur at any age, and affects men and women equally.
Most people affected with this syndrome seek medical treatment because of one of the following: peptic ulcer disease, symptoms related to low blood sugar, symptoms related to high serum calcium levels or kidney stones, or symptoms related to pituitary problems such as headache.
Risk factors are a family history of this disorder, a previous pituitary tumor, and a history of Zollinger-Ellison syndrome.
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• Definition
• Overview, Causes, & Risk Factors
• Symptoms & Signs
• Prevention
• Diagnosis & Tests
• Treatment
• Prognosis
• Complications
• Calling Your Health Care Provider
• Pictures & Images
Topics that might be of interest to you Diseases & Conditions
• Hypoglycemia
• Infertility
• Nephrolithiasis
• Peptic Ulcer
• Pituitary Tumor
• Tumor
• Zollinger-Ellison Syndrome
Tests & Exams
• Abdominal CT Scan
• Abdominal MRI
• ACTH
• Calcium - Ionized
• Cortisol Level
• Cranial CT Scan
• FSH
• Glucagon
• Glucose Test
• Hyperplasia
• Insulin Test
• LH Blood Test
• MRI of the Head
• Parathyroid Biopsy
• PTH
• Serum Calcium
• TSH
Other Topics
• Abdominal Bloating
• Abdominal Pain
• Appetite - Decreased
• Appetite - Increased
• Benign
• Blood Pressure - Low
• Bloody or Tarry Stools
• Cold Intolerance
• Confusion
• Consciousness - Decreased
• Erection Problems
• Fatigue
• Headache
• Menstruation - Absent
• Movement - Uncoordinated
• Muscle Aches
• Nausea and Vomiting
• Stress and Anxiety
• Vision Problems
• Weakness
• Weight Loss - Unintentional
Review Date : 5/2/2003
Reviewed By : Ezra E. W. Cohen, M.D., Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL. Review provided by VeriMed Healthcare Network.
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