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Mesothelioma (Malignant)
DefinitionMalignant mesothelioma is a cancerous tumor of the pleura (lining of the lung and chest cavity) or peritoneum (lining of the abdomen) that is almost always caused by sustained exposure to asbestos.
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Overview, Causes, & Risk Factors
Malignant mesothelioma is a diffuse tumor that affects men more frequently than women. Sustained exposure to asbestos is the predominant risk factor. However, smoking dramatically increases risk amongst the asbestos-exposed. The latent period between asbestos exposure and onset of symptoms can be 20 to 50 years or even longer.
The median age of diagnosis is 60. The tumor can spread rapidly to involve the pericardium (sac around the heart), mediastinum, and opposite pleura. Progressive pain and shortness of breath can occur. The tumor is usually associated with a pleural effusion.
Differentiation of the tumor from other conditions of the pleura and other types of cancer can be difficult, even when experienced pathologists are viewing biopsy samples.
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• Definition
• Overview, Causes, & Risk Factors
• Symptoms & Signs
• Prevention
• Diagnosis & Tests
• Treatment
• Prognosis
• Complications
• Support Groups
• Calling Your Health Care Provider
• Pictures & Images
Topics that might be of interest to you Diseases & Conditions
• Pleural Effusion
• Tumor
Tests & Exams
• Chest X-Ray
• Open Lung Biopsy
• Thoracic CT
Other Topics
• Breathing Difficulty
• Cancer - Resources
• Chest Pain
• Cough
• Lung Disease - Resources
• Resources
• Stress and Anxiety
• Weight Loss - Unintentional
Review Date : 9/9/2002
Reviewed By : Kevin Knopf, M.D., M.P.H., Hematologist/Oncologist and Director of Clinical Research, Annapolis Oncology/Hematology Center, Annapolis, MD. Review provided by VeriMed Healthcare Network.
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