Membranoproliferative GN I
Alternate Names : Glomerulonephritis - Membranoproliferative (Type I), Lobular GN, Membranoproliferative Glomerulonephritis (Type I), Mesangiocapillary Glomerulonephritis (Type I), MPGN Type I
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Treatment
Treatment may vary according to the symptoms. Treatment goals include reduction of symptoms, prevention of complications, and slowed progression of the disorder. Steroids and cytotoxic agents have been used and may benefit certain individuals. Dipyridamole has also been used in some individuals.
Dietary adjustments may include restrictions on sodium (see sodium in diet), fluids, protein, or other restrictions as appropriate to control high blood pressure, swelling, and accumulation of waste products in the bloodstream.
Antihypertensive medications are critical to help control blood pressure. Diuretics or other medications may be appropriate to control edema or other symptoms.
Dialysis or kidney transplant may eventually be required to manage renal failure. Combination therapy with aspirin and dipyridamole may slow progression to renal failure with MPGN 1. This treatment is of unproven value.
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