Lupus anticoagulants

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Lupus anticoagulants

Definition

Lupus anticoagulants are antibodies against phospholipids (substances in the lining of cells) that prevent blood clotting in a test tube. Persons with these antibodies may have an abnormally high risk of blood clotting.

Overview, Causes, & Risk Factors

Lupus anticoagulants are usually found in persons with autoimmune diseases, such as systemic lupus erythematosus (SLE).

They may also be found in persons who take certain medications, including phenothiazines, phenytoin, hydralazine, quinine, and the antibiotic amoxicillin.

Persons with inflammatory bowel disease (Crohn's disease and ulcerative colitis), infections, and certain tumors may have lupus anticoagulants.

Some people have no risk factors for this condition. In some cases, SLE is linked to an increased risk of blood clots and may be the cause of recurrent miscarriages.

Pictures & Images

Systemic lupus erythematosus rash on the face

Blood clots

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Lupus anticoagulants : Definition
Lupus anticoagulants : Overview, Causes, & Risk Factors
Lupus anticoagulants : Symptoms & Signs
Lupus anticoagulants : Diagnosis & Tests
Lupus anticoagulants : Treatment
Lupus anticoagulants : Prognosis (Expectations)
Lupus anticoagulants : Complications
Lupus anticoagulants : Calling Your Health Care Provider
Lupus anticoagulants : Prevention
Lupus anticoagulants : References
Lupus anticoagulants : Pictures & Images
Systemic lupus erythematosus rash on the face
Blood clots

Review Date : 1/12/2009
Reviewed By : Todd Gersten, M.D., Hematology/Oncology, Palm Beach Cancer Institute, West Palm Beach, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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