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You are here : AllRefer.com > Health > Diseases & Conditions > Lambert-Eaton syndrome

Lambert-Eaton syndrome

Alternate Names : Myasthenic syndrome, Eaton-Lambert syndrome

Definition

Lambert-Eaton syndrome is a disorder in which faulty communication between nerves and muscles leads to muscle weakness .

Overview, Causes, & Risk Factors

Lambert-Eaton syndrome occurs when nerves cells do not release enough of a chemical called acetylcholine, which transmits impulses between nerves and muscles.

The result is muscle weakness and other symptoms similar to myasthenia gravis. However, as the muscles continue to contract, the chemical (acetylcholine) can build up in sufficient quantities for strength to get slightly better.

Lambert-Eaton syndrome may be associated with cancers such as small-cell lung cancer and autoimmune disorders.

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Superficial anterior muscles
Superficial anterior muscles

       
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Review Date : 9/16/2008
Reviewed By : Daniel B. Hoch, PhD, MD, Assistant Professor of Neurology, Harvard Medical School, Department of Neurology, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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