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Hypothyroidism
Alternate Names : Adult Hypothyroidism, Myxedema
Definition
Hypothyroidism is a condition in which the thyroid gland fails to produce enough thyroid hormone.
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Overview, Causes, & Risk Factors
The thyroid gland, located in the front of the neck just below the larynx, secretes hormones that control metabolism. These hormones are thyroxine (T4) and triiodothyronine (T3).
The secretion of T3 and T4 is controlled by the pituitary gland and the hypothalamus, which is part of the brain. Thyroid disorders may result not only from defects in the thyroid gland itself, but also from abnormalities of the pituitary or hypothalamus. Hypothyroidism, or underactivity of the thyroid gland, may cause a variety of symptoms and may affect all body functions. The body's normal rate of functioning slows, causing mental and physical sluggishness. The symptoms may vary from mild to severe, with the most severe form called myxedema, which is a medical emergency.
The most common cause of hypothyroidism is Hashimoto's thyroiditis, a disease of the thyroid gland where the body's immune system attacks the gland. Failure of the pituitary gland to secrete a hormone to stimulate the thyroid gland (secondary hypothyroidism) is a less common cause of hypothyroidism. Other causes include congenital defects, surgical removal of the thyroid gland, irradiation of the gland, or inflammatory conditions. Risk factors include age over 50 years, female gender, obesity, thyroid surgery, and exposure of the neck to x-ray or radiation treatments.
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Definition Hypothyroidism Overview, Causes, & Risk Factors Hypothyroidism Symptoms & Signs Hypothyroidism Prevention Hypothyroidism Diagnosis & Tests Hypothyroidism Treatment Hypothyroidism Prognosis Hypothyroidism Complications Calling Your Health Care Provider
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Tests & Exams
CBC Chest X-Ray Prolactin Pulse Serum Sodium T3 T4 Test TSH X-Ray
Other Topics
Agitation Blood Pressure - Low Chest Pain Cold Intolerance Consciousness - Decreased Constipation Depression Drowsiness Dry Hair Dry Skin Facial Swelling Fatigue Foot, Leg, and Ankle Swelling Hair Loss Hoarseness or Changing Voice Hypothalamus Intravenous Joint Pain Menstrual Periods - Heavy, Prolonged, or Irregular Menstruation - Absent Metabolism Movement - Uncoordinated Muscle Aches Muscle Atrophy Muscle Cramps Nail Abnormalities Obesity Paleness Physical Examination Short Stature Sweating - Excessive Swelling Taste - Impaired Vital Signs Weakness Weight Gain - Unintentional Weight Loss - Unintentional
Review Date : 5/10/2002
Reviewed By : Stephanie Fish, M.D., Division of Endocrinology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
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