Herpes Simplex - Close-Up

This close-up view of early herpes outbreak shows small, grouped blisters (vesicles) and lots of inflammation (erythema).

Erythema Multiforme on the Leg

The red spots on this person's back appear where blisters (bullae) caused by Erythema multiforme have ruptured and the overlying skin removed (denuded). The resulting lesions are yellow-crusted ulcers (erosions). Erythema multiforme may be associated with herpes simplex infection, mycoplasma pneumonia, or other medical conditions such as streptococcal infection, tuberculosis (TB), or may result from exposure to chemicals or medications.

Erythema Multiforme on the Hand

This individual has erythema multiforme minor, with "target" lesions on his hands. His condition may result from a recurrent herpes simplex virus infection on the lip.