Hepatorenal syndrome is a condition in which the kidneys fail suddenly in a person with cirrhosis of the liver. It is a serious complication of cirrhosis.
Overview, Causes, & Risk Factors
Hepatorenal syndrome occurs when there is a decrease in kidney function in a person with a liver disorder. Because less urine is removed from the body, nitrogen-containing waste products build up in the bloodstream (azotemia).
The disorder occurs in up to 10% of patients hospitalized with liver failure. It is caused by the built-up effects of liver damage and kidney failure in people with:
Other risk factors include:
- Blood pressure that falls when a person rises or suddenly changes position (orthostatic hypotension)
- Diuretic use
- Gastrointestinal bleeding
- Recent abdominal paracentesis
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