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Focal Segmental Glomerulosclerosis
Alternate Names : Focal Sclerosis with Hyalinosis, Segmental Glomerulosclerosis
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Treatment
The goal of treatment is to control the symptoms associated with nephrotic syndrome and chronic renal failure. Treatment may be chronic and lifelong.
Corticosteroids and immunosuppressive medications may be prescribed to reduce the immune response.
Medicines to treat high blood pressure, especially a group of drugs called angiotensin converting enzyme inhibitors, and diuretics may help control symptoms such as high blood pressure and edema. Antibiotics may be needed to control infections.
Your doctor may treat high blood cholesterol and triglyceride levels, which are also common with this disorder, to reduce the development of atherosclerosis. Reducing cholesterol and saturated fats in the diet may be of only limited benefit as the high levels seen in this condition seem to result from overproduction of cholesterol and triglycerides by the liver rather than the excessive intake of fats. Medicines to reduce cholesterol and triglycerides may be recommended.
In most cases, a moderate-protein diet (1 gram of protein per kilogram of body weight per day) is usually recommended. In cases where renal failure is present, a low-protein diet may be preferred.
Sodium (salt) in the diet and fluids may be restricted to help control swelling (see also renal disease - diet). Vitamin D may need to be supplemented if nephrotic syndrome is chronic and unresponsive to therapy.
Dialysis or kidney transplantation may be necessary to control renal failure.
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Definition Overview, Causes, & Risk Factors Symptoms & Signs Prevention Diagnosis & Tests Treatment Prognosis Complications Calling Your Health Care Provider
Pictures & Images
Topics that might be of interest to you Diseases & Conditions
Atherosclerosis Chronic Renal Failure End-Stage Kidney Disease Lipid Disorders - Acquired Nephrotic Syndrome Reflux Nephropathy
Tests & Exams
Blood Pressure Dialysis Immunofluorescence Protein - Urine Renal Biopsy Triglyceride Level Urinalysis
Other Topics
Cholesterol Chronic Diet - Chronic Kidney Disease Fever Immune Response Sodium in Diet Swelling Urination - Painful Urine Output - Decreased Vitamin D
Review Date : 8/7/2003
Reviewed By : Irfan A. Agha, M.D., Department of Medicine, Renal Division, St. Louis University, St. Louis, MO. Review provided by VeriMed Healthcare Network.
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