Familial dysbetalipoproteinemia (Type III hyperlipoproteinemia, Deficient or defective apolipoprotein E)

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Familial dysbetalipoproteinemia

Alternate Names : Type III hyperlipoproteinemia, Deficient or defective apolipoprotein E

Definition

Familial dysbetalipoproteinemia is a disorder passed down through families in which there are high amounts of cholesterol and triglycerides in the blood.

Overview, Causes, & Risk Factors

A genetic defect causes this condition. The defect results in the buildup of large lipoprotein particles that contain both cholesterol and triglycerides, a type of fat. The disease is linked to defects in the gene for apolipoprotein E in many cases.

Hypothyroidism, obesity, or diabetes can make the condition worse. Risk factors for familial dysbetalipoproteinemia include a family history of the disorder or coronary artery disease.

Pictures & Images

Coronary artery disease

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Familial dysbetalipoproteinemia : Definition
Familial dysbetalipoproteinemia : Overview, Causes, & Risk Factors
Familial dysbetalipoproteinemia : Symptoms & Signs
Familial dysbetalipoproteinemia : Diagnosis & Tests
Familial dysbetalipoproteinemia : Treatment
Familial dysbetalipoproteinemia : Prognosis (Expectations)
Familial dysbetalipoproteinemia : Complications
Familial dysbetalipoproteinemia : Calling Your Health Care Provider
Familial dysbetalipoproteinemia : Prevention
Familial dysbetalipoproteinemia : Pictures & Images
Coronary artery disease

Review Date : 1/23/2008
Reviewed By : Glenn Gandelman, MD, MPH, Assistant Clinical Professor of Medicine, New York Medical College, Valhalla, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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