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Factor X Deficiency
Alternate Names : Stuart-Prower Deficiency
Definition Factor X deficiency is a disorder that causes abnormal blood clotting (coagulation), resulting from a shortage of a plasma protein called factor X.
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Overview, Causes, & Risk Factors
Normal blood coagulation is a complex process involving as many as 20 different plasma proteins, which are known as blood coagulation factors. A series of complex chemical reactions using these factors takes place very rapidly to form an insoluble protein called fibrin that stops bleeding.
When certain coagulation factors are deficient or missing, the chain reaction does not take place normally. Factor X deficiency is often caused by an inherited defect of the factor X gene, and bleeding ranges from mild to severe. Another cause of factor X deficiency is amyloidosis (a disorder in which insoluble protein fibers deposit in tissues and organs, impairing their function).
Women with this condition may have severe menstrual bleeding and bleeding after delivery. Newborn boys with the condition may have prolonged bleeding after circumcision.
The incidence is 1 out of 500,000.
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Definition Factor X Deficiency Overview, Causes, & Risk Factors Factor X Deficiency Symptoms & Signs Factor X Deficiency Prevention Factor X Deficiency Diagnosis & Tests Factor X Deficiency Treatment Factor X Deficiency Prognosis Factor X Deficiency Complications Factor X Deficiency Support Groups Calling Your Health Care Provider
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Topics that might be of interest to you Diseases & Conditions
Bleeding Disorders Primary Amyloidosis
Tests & Exams
Factor X Assay Partial Thromboplastin Time (PTT) Prothrombin Time (PT)
Other Topics
Acute Bleeding Hemophilia - Resources Incidence Mucosa Muscle Cramps Nosebleed Injury Protein in Diet Resources Stress and Anxiety
Review Date : 8/18/2003
Reviewed By : Corey Cutler, M.D., M.P.H., F.R.C.P.C, Department of Medical Oncology, Dana-Farber Cancer Institute; Instructor in Medicine, Harvard University, Boston, MA. Review provided by VeriMed Healthcare Network.
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