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Factor V Deficiency
Alternate Names : Owren's Disease, Parahemophilia
DefinitionFactor V deficiency is an inherited abnormal bloodcoagulation disorder caused bya deficiency of the plasma protein Factor V.
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Overview, Causes, & Risk Factors
Normal blood coagulation is a complex process involving as many as 20 different plasma proteins, which are known as blood coagulation factors. A series of complex chemical reactions using these factors takes place very rapidly to form an insoluble protein called fibrin that stops bleeding.
When certain coagulation factors are deficient or missing, the chain reaction does not take place normally. Factor V deficiency is caused by inheriting a defective Factor V gene. In this disorder, bleeding ranges from mild to severe.
The disease is similar to hemophilia, except bleeding into joints is less common. Bleeding can occur almost anywhere in the body, and death from hemorrhage has occurred with this disorder.
Excessive bleeding with menstrual periods and after delivery occurs frequently. A family history of a bleeding disorder is a risk factor. Men and women are affected equally, and the incidence is about 1 in 1 million.
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• Definition
• Factor V Deficiency Overview, Causes, & Risk Factors
• Factor V Deficiency Symptoms & Signs
• Factor V Deficiency Prevention
• Factor V Deficiency Diagnosis & Tests
• Factor V Deficiency Treatment
• Factor V Deficiency Prognosis
• Factor V Deficiency Complications
• Factor V Deficiency Support Groups
• Calling Your Health Care Provider
• Pictures & Images
Topics that might be of interest to you Diseases & Conditions
• Bleeding Disorders
• Hemophilia
Tests & Exams
• Bleeding Time
• Factor V Assay
• Partial Thromboplastin Time (PTT)
• Prothrombin Time (PT)
Other Topics
• Bleeding
• Bleeding Gums
• Bleeding Into the Skin
• Menstrual Periods - Heavy, Prolonged, or Irregular
• Nosebleed Injury
• Protein in Diet
Review Date : 5/6/2002
Reviewed By : Rebecca Elstrom, M.D., Division of Hematology-Oncology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network (10/14/2001).
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