Essential Tremor

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Overview, Causes, & Risk Factors

All people have some degree of tremor that occurs during movement,. This shaking is called physiologic (occurs normally), and it mainly involves the hands. Stressful circumstances, such as fatigue, anger, fear or using certain substances (such as coffee or cigarettes) may cause transient worsening of physiologic tremor, to the point that it may become visible to the naked eye.

Essential tremor is the most common form of abnormal tremor, which resembles an exaggerated physiologic shaking. Essential tremor is worsened by the same factors that enhance physiologic tremor. Although the cause is unknown, new research shows that one part of the brain called cerebellum does not appear to function properly in patients who have essential tremor. The cerebellum is the part of the brain that coordinates muscle movements and therefore, provides accuracy and harmony to voluntary movement. Nevertheless, no evident brain lesions have been identified in patients with this form of tremor.

There is evidence that there are several different types of essential tremor (such as young-onset essential tremor or essential tremor with head tremor). These types differ in their response to treatment.

If an essential tremor occurs in more than one member within a family group, it is termed a familial tremor. It therefore appears that essential tremor has some genetic basis, not only because of the hereditary pattern observed in some families, but also because the identical twin (who shares the same genetic makeup) of a person with essential tremor are twice as likely as a fraternal twin (who typically shares the same number of genes as other siblings) to have essential tremor.

Since some identical twins do not share this condition, environmental factors must play a role as well. Essential tremors can occur at any age but are most common in people older than 65.

Essential tremor is a relatively benign condition, affecting movement or voice quality, but with no other effects. It involves a rhythmic, moderately rapid tremor of voluntary muscles. Purposeful movements may make the tremors worse, while avoiding hand movements may suppress the tremors completely. There may be difficulty holding or using small objects (such as silverware or writing utensils).

Over time, the tremors may affect the hands, arms, head, voice box (larynx), eyelids, or other muscles. An essential tremor rarely involves the legs or feet. It may start in one body part but can progress to include other parts with time.