Dilutional Hyponatremia (SIADH)
Alternate Names : SIADH, Syndrome of Inappropriate Antidiuretic Hormone Secretion
DefinitionDilutional hyponatremia is a disorder of fluid and electrolyte balance caused by excessive release of antidiuretic hormone (ADH).
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Overview, Causes, & Risk Factors
Fluid and electrolyte imbalance in this syndrome result from the inability to excrete dilute urine, retention of water within the body, and low sodium levels. The most common cause of SIADH is a type of lung cancer called "oat cell" or small cell, which secretes excessive ADH.
Other causes are pancreatic cancer, prostate cancer, Hodgkin's disease, central nervous system disorders, pulmonary disorders, certain drugs, thymomas, myxedema, and psychosis. SIADH may also develop in some children during the acute phase of meningitis. Risk factors are related to the causes.
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