Cushing's Syndrome - Adrenal Tumor
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Treatment
Cushing's syndrome due to an adrenal tumor is treated by surgical removal of the tumor (which often includes removal of the gland as well). Glucocorticoid replacement therapy is usually required until the other adrenal gland recovers from surgery. Nine to 12 months of glucocorticoid therapy may be required.
If surgery is not possible, particularly with cases of adrenal carcinoma, medications can suppress the secretion of cortisol:
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Mitotane
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Ketoconazole
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Aminoglutethimide
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Metyrapone
Radiation therapy is rarely effective in patients with adrenal carcinoma and is usually not appropriate for adrenal adenoma.
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