Crigler-Najjar Syndrome
Alternate Names : Arias Syndrome (Type II Crigler-Najjar), Glucuronyl Transferase Deficiency (Type I Crigler-Najjar)
Definition
Crigler-Najjar syndrome is an inherited disorder in which bilirubin (a substance made by the liver) cannot be changed into its water-soluble form, bilirubin glucuronide. This causes jaundice (yellow discoloration of skin and eyes) and organ malfunctions.
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