Creatinine clearance
Risks
The risks of the test are minimal and are related to the blood draw process. Rarely, the following will occur: - Excessive bleeding at blood draw site
- Fainting or feeling light-headed
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
- Multiple punctures to locate veins
Special Considerations
Factors that may interfere with the accuracy of the test are as follows: - Incomplete urine collection
- Pregnancy
- Vigorous exercise
Drugs that can interfere with creatinine clearance measurements include: cimetidine, trimethoprim, and drugs that can damage the kidneys, such as cephalosporins. The creatinine clearance test should only be done for patients who are medically stable. Such patients may have a rapidly changing creatinine clearance, and therefore any result may be inaccurate.
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