Coombs' Test - Indirect
Alternate Names : Indirect Antiglobulin Test
Definition
The indirect Coombs' test measures the presence of antibodies to red blood cells in the blood (see also Coombs' test - direct).
Why is the Test Performed?
The indirect Coombs' test detects circulating antibodies against red blood cells (RBCs). The major use of this test is to determine if the patient has antibodies in the blood capable of attaching to RBCs. (These antibodies are other than the major ABO system or the Rh type).
The test is only rarely used to diagnose a medical condition but is essential for use by laboratories such as blood banks. Blood banks use the indirect Coombs' test is to determine whether there is likely to be an adverse reaction to blood that is going to be used for a blood transfusion.
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