Chronic Pancreatitis
DefinitionChronic pancreatitis involves persistent inflammation of the pancreas -- an elongated, tapered gland that is located behind the stomach and secretes digestive enzymes and the hormones insulin and glucagon.
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Overview, Causes, & Risk Factors
Chronic pancreatitis is most often caused by alcoholism and alcohol abuse, but sometimes the cause cannot be determined. Conditions such as hyperlipidemia or hyperparathyroidism, injury, and chronic obstruction of the pancreatic duct can also be associated with chronic pancreatitis.
In this condition, inflammation and fibrosis cause the destruction of functioning glandular tissue in the pancreas. The resulting lack of pancreatic enzymes interferes with the ability to properly digest fat. The production of insulin is also affected, which can lead to diabetes.
This condition is marked by attacks of abdominal pain and digestive problems that may become more frequent as the condition progresses. Chronic pancreatitis occurs more frequently in men than in women, perhaps because alcohol use disorders are more common in men.
Note: pancreatic cancer can cause symptoms and signs that are similar to those of chronic pancreatitis.
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