Cholestasis
Alternate Names : Intrahepatic cholestasis, Extrahepatic cholestasis
Definition
Cholestasis is any condition in which the flow of bile from the liver is blocked.
Overview, Causes, & Risk Factors
There are many causes of cholestasis. Extrahepatic cholestasis occurs outside the liver. It can be caused by: - Bile duct tumors
- Cysts
- Narrowing of the bile duct (strictures)
- Stones in the common bile duct
- Pancreatitis
- Pancreatic tumor or pseudocyst
- Pressure on an organ due to a nearby mass or tumor
- Primary sclerosing cholangitis
Intrahepatic cholestasis occurs inside the liver. It can be caused by: - Alcoholic liver disease
- Amyloidosis
- Bacterial abscess in the liver
- Being fed through a vein (IV)
- Lymphoma
- Pregnancy
- Primary biliary cirrhosis
- Primary sclerosing cholangitis
- Sarcoidosis
- Serious infections that have spread through the bloodstream (sepsis)
- Tuberculosis
- Viral hepatitis
- Sjogren syndrome
Certain medications can also cause cholestasis. See: Drug-induced cholestasis
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