Apolipoprotein CII
Alternate Names : ApoCII, Apoprotein CII
Definition
Lipoproteins are large complexes of molecules that transport lipids (primarily triglycerides and cholesterols) through the blood. Apolipoproteins are proteins on the surface of the lipoprotein complex that bind to specific enzymes or transport proteins on the cell membranes. This directs the lipoprotein to the proper site of metabolism.
Apolipoprotein CII (apoCII) is in found in chylomicrons (large lipoprotein particles absorbed from the gastrointestinal tract) and VLDL (large lipoproteins that are broken down to eventually form LDL). ApoCII activates the enzyme that breaks down chylomicron and VLDL molecules.
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Why is the Test Performed?
This test is usually performed to help determine the cause of hyperlipidemia (elevated blood lipid levels).
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