Anencephaly
Alternate Names : Aprosencephaly with Open Cranium
Definition
Anencephaly is the absence of a large part of the brain and the skull.
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Overview, Causes, & Risk Factors
Anencephaly is a neural tube defect that occurs early in the development of an unborn baby. Neural tube defects involve the tissue that grows into the brain and spinal cord. Anencephaly results when the upper portion of the neural tube fails to close. Why this happens is not known. Possible causes include environmental toxins and low intake of folic acid during pregnancy.
Anencephaly occurs in about 4 out of 10,000 births. The exact number is unknown, because many of these pregnancies spontaneously abort. Having one anencephalic infant increases the risk of having another child with neural tube defects.
Low intake of folic acid during pregnancy can also contribute to neural tube defects such as anencephaly.
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