Anemia - B12 deficiency
Alternate Names : Macrocytic anemia
Definition
Anemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. Vitamin B12 deficiency anemia is a low red blood cell count due to a lack of vitamin B12. See also:
Overview, Causes, & Risk Factors
Your body needs vitamin B12 to make red blood cells. In order to provide vitamin B12 to your cells: - You must eat enough foods that contain vitamin B12, such as meat, poultry, shellfish, eggs, and dairy products.
- Your body must absorb enough vitamin B12. Your body uses a special protein, called intrinsic factor, released by cells in the stomach. The combination of vitamin B12 attached to intrinsic factor is absorbed in the last part of the small intestine.
A lack of vitamin B12 in the diet may be due to: - Eating a vegetarian diet
- Poor diet in infancy
- Poor nutrition during pregnancy
A number of problems can make it difficult for your body to absorb enough vitamin B12: - Chronic alcoholism
- Crohn's disease, celiac disease, infection with the fish tapeworm, or other problems that make it difficult for your body to digest foods
- Pernicious anemia, which occurs when your body destroys cells that make intrinsic factor. Intrinsic factor is needed to absorb vitamin B12.
- Surgeries that remove certain parts of your stomach or small intestine, such as some weight-loss surgeries
- Taking antacids and other heartburn medicines for a long period of time
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