Anaphylaxis is an emergency condition requiring immediate professional medical attention. Call 911 immediately.

Check the ABCs (airway, breathing, and circulation from Basic Life Support) in all suspected anaphylactic reactions.

CPR should be started, if needed. People with known severe allergic reactions may carry an Epi-Pen or other allergy kit, and should be helped if necessary.

Paramedics or physicians may place a tube through the nose or mouth into the airways (endotracheal intubation) or perform emergency surgery to place a tube directly into the trachea (tracheostomy or cricothyrotomy).

Epinephrine should be given by injection in the thigh muscle right away. This opens the airways and raises the blood pressure by tightening blood vessels.

Treatment for shock includes fluids through a vein (intravenous) and medications that support the actions of the heart and circulatory system.

The person may receive antihistamines, such as diphenhydramine, and corticosteroids, such as prednisone, to further reduce symptoms (after lifesaving measures and epinephrine are administered).

Anaphylaxis is a severe disorder that can be life-threatening without prompt treatment. However, symptoms usually get better with the right therapy, so it is important to act right away.

• Airway blockage
• Cardiac arrest (no effective heartbeat)
• Respiratory arrest (no breathing)
• Shock

Call 911 if you develop severe symptoms of anaphylaxis. If you are with another person, he or she may take you to the nearest emergency room.