Alport syndrome (Hereditary nephritis, Hematuria - nephropathy - deafness, Hemorrhagic familial nephritis, Hereditary deafness and nephropathy)

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Alport syndrome

Alternate Names : Hereditary nephritis, Hematuria - nephropathy - deafness, Hemorrhagic familial nephritis, Hereditary deafness and nephropathy

Definition

Alport syndrome is an inherited disorder that damages tiny blood vessels in the kidneys.

Overview, Causes, & Risk Factors

Alport syndrome is an inherited form of kidney inflammation (nephritis). It is caused by a mutation in a gene for a protein in connective tissue, called collagen.

The disorder is uncommon, and most often affects males. Women can transmit the gene for the disorder to their children, even if they have no symptoms.

Risk factors include:

End-stage kidney disease in male relatives
Family history of Alport syndrome
Glomerulonephritis
Hearing loss before age 30
Nephritis

Pictures & Images

Male urinary system

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Alport syndrome : Definition
Alport syndrome : Overview, Causes, & Risk Factors
Alport syndrome : Symptoms & Signs
Alport syndrome : Diagnosis & Tests
Alport syndrome : Treatment
Alport syndrome : Prognosis (Expectations)
Alport syndrome : Complications
Alport syndrome : Calling Your Health Care Provider
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Male urinary system

Review Date : 11/30/2009
Reviewed By : David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Herbert Y. Lin, MD, PHD, Nephrologist, Massachusetts General Hospital; Associate Professor of Medicine, Harvard Medical School. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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